The impact of kidney function on the slow-flow/no-reflow phenomenon in patients treated with primary percutaneous coronary intervention: registry analysis

Abstract Funding Acknowledgements Type of funding sources: None. Objective To analyze the impact declining kidney function on occurrence slow-flow/no-reflow phenomenon, in patients with ST elevation myocardial infarction (STEM) who had been treated primary PCI (pPCI), and to prognostic phenomenon short- long-term mortality these patients. Methods We analyzed 3,115 consecutive A value estimation glomerular filtration rate (eGFR) at admission eGFR<90ml/min/m2 was considered be a reduced baseline eGFR. The follow-up period 8 years. Results through IRA registered 146 (4.7%) Stimated GFR<90ml/min/m2 an independent predictor for (OR2.91, 95%CI 1.25-3.95, p<0.001), risk increased decline function: eGFR 60-89 ml/min/m2: OR1.94 (95%C 1.22-3.07, p=0.005), 45-59ml/min/m2: OR 2.55(95%CI 1.55-4.94, 30-44 ml/min/m2; 2.77(95%CI 1.43-5.25, 15-29 5.84 (95%CI 2.84-8.01, p<0.001). In-hospital, 30-day, 1-year, 8-year were significantly higher as compared TIMI flow grade 3 – in-hospital 30.1% vs 2.9%, respectively, p<0.001; 30-day mortality: 31.5% 3.2%, 38.1% 6.9%, p<0.001 (Figure 1). strong short-and all-cause (HR 2.62, 1.78-3.57, 2.09, 1.49-2.09, Conclusion Reduced its started mildest decrease (below 90ml/min/m2), further decline.